Current Issue: September 2026
Feature
Therapeutic Drug Monitoring in Adolescents and Children With Inflammatory Bowel Disease
Abstract: Proactive longitudinal therapeutic drug monitoring (TDM) is the standard of care for pediatric patients with inflammatory bowel disease (IBD). This is important because children and […]
Case Study in IBS-C
QOL-Guided Decision-Making to Switch Mechanism of Action in IBS-C: Applying JUST ASK Study Principles in Clinical Practice
About the Patient JS, a 38-year-old man, presented with long-standing complaints of persistent bloating, abdominal distension, constipation, incomplete evacuation, and reduced quality of life. He had […]
Advances in Hepatology
Update on Treatment for Hepatitis Delta
G&H Before the recent drug approval for hepatitis delta, how was this disease treated? TK Prior to the approval of bulevirtide (Hepcludex, Gilead) by the US […]
Advances in IBD
Dose Optimization of Interleukin-23 Inhibitor Therapies in Inflammatory Bowel Disease
G&H How are the pharmacokinetics and pharmacodynamics of interleukin-23 inhibitors similar to or different from other biologics in inflammatory bowel disease? GL Interleukin (IL)-23 inhibitors differ […]
Advances in Endoscopy
Colonoscopy vs Stool-Based Testing for Colorectal Cancer Detection
G&H What is the current status of colorectal cancer screening in the United States, and what screening tests are recommended? JD Based on colorectal cancer (CRC) […]
Advances in IBS
GLP-1 RAs and Their Potential to Aggravate or Ameliorate Gastrointestinal Symptoms in IBS
G&H What are the effects of glucagon-like peptide-1 receptor agonists in the gastrointestinal tract? MC Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) affect the motor function and […]
Letter From the Editor
Letter From the Editor: Optimizing Interleukin-23 Inhibitor Dosing in Inflammatory Bowel Disease
How can clinicians navigate dose optimization of interleukin (IL)-23 inhibitor therapies in patients with inflammatory bowel disease (IBD)? This question is explored in my Advances in […]
MASH in Focus
Prognostic Value of Liver Stiffness Measurement by VCTE in MASLD/MASH
G&H What is the prognostic accuracy of vibration-controlled transient elastography–based liver stiffness measurement for predicting liver-related events in metabolic dysfunction-associated steatotic liver disease, compared with using […]