Highlights From the Recent AASLD Practice Guidelines on Noninvasive Assessment of Hepatic Fibrosis and Steatosis

G&H Why were guidelines recently released on noninvasive assessment of hepatic fibrosis and steatosis, and how were they developed? RS Understanding the fibrosis stage is paramount […]

Overview of Pruritus Management in Patients With Chronic Liver Disease

G&H How common is pruritus in patients with chronic liver disease? AB Overall, the incidence of pruritus or itching in patients with chronic liver disease has […]

Current Management of Patients With Alcohol-Associated Hepatitis

G&H How has alcohol use changed since the COVID-19 pandemic? BL Heavy alcohol use had been declining before the COVID-19 pandemic. The pandemic saw a significant […]

Update on Transjugular Intrahepatic Portosystemic Shunt Use in Liver Disease

G&H Which patients should be considered for early use of a transjugular intrahepatic portosystemic shunt? JB There has been some movement away from previous practice approximately […]

Perioperative Risk in Patients With Cirrhosis

G&H Why do patients with cirrhosis have an increased risk of perioperative morbidity and mortality? KJ Patients with cirrhosis typically have hepatocellular dysfunction and portal hypertension, […]

Frailty, Sarcopenia, and Nutrition in Patients With Cirrhosis

G&H Why is it important to identify frailty and sarcopenia in patients with cirrhosis? JL Frailty and sarcopenia are unfortunately prevalent in patients with cirrhosis. Up […]

Current and Emerging Treatments for Autoimmune Hepatitis

G&H What is the current understanding of autoimmune hepatitis and its pathogenesis? EW Autoimmune hepatitis (AIH) is a composite of diseases marked by immune dysregulation targeting […]

Reflecting on a Decade of Sofosbuvir Use for Hepatitis C Virus Treatment

G&H Sofosbuvir was approved with ribavirin or pegylated interferon plus ribavirin just over 10 years ago for the treatment of hepatitis C virus infection. Thinking back […]

Highlights From the ACG Guidelines for Acute Liver Failure

G&H Why were guidelines recently released for acute liver failure? AS The previous North American guidelines on acute liver failure had been released over a decade […]

Preventative Hepatology and the Reduction of All-Cause Mortality in Liver Disease

G&H Why is preventative hepatology important and a growing area of study and interest? JP Preventative hepatology is important because so much of chronic liver disease […]

Delta Hepatitis in the United States: Epidemiology, Testing, and Linkage to Care

G&H What is the current prevalence of delta hepatitis in the United States and worldwide? RG Delta hepatitis, also known as hepatitis delta virus (HDV), requires […]

Social Media and Hepatology

G&H Why should hepatologists and physicians in general engage in social media at all? JW There are many reasons to engage in social media as a […]

Pain Management in Liver Disease

G&H How prevalent are acute and chronic pain in patients with liver disease, and what are the most common sources of pain in this setting? JH […]

Examining the New Definition of Hepatorenal Syndrome and the Role of Terlipressin

G&H How common is hepatorenal syndrome, and what are its potential consequences? RB Hepatorenal syndrome is the most serious complication of cirrhosis and portal hypertension and […]

Pregnancy and Hepatitis C Virus

G&H What is the prevalence of hepatitis C virus in pregnant women, and why has it been increasing recently in the United States? TK A number […]

Screening for Cholangiocarcinoma in Patients With Primary Sclerosing Cholangitis

G&H What is the risk of developing cholangiocarcinoma in patients with primary sclerosing cholangitis? JL Primary sclerosing cholangitis (PSC) is a rare chronic autoimmune and cholestatic […]

Overview of Liver Involvement in Patients With Erythropoietic Protoporphyria

G&H How does erythropoietic protoporphyria differ from other porphyrias, and what are its most common signs and symptoms? CL Erythropoietic protoporphyria (EPP) is a rare genetic […]

Use of Angiotensin-Converting Enzyme Inhibitors in Patients With Liver Disease

G&H How do angiotensin-converting enzyme inhibitors work, and can they have an effect on liver disease? ET Angiotensin-converting enzyme (ACE) inhibitors block an enzyme that increases […]

Gamma-Glutamyl Transferase in Patients With Primary Biliary Cholangitis

G&H What are the possible causes for elevations of gamma-glutamyl transferase? AG Although many factors can cause elevations of gamma-glutamyl transferase (GGT), this enzyme is mainly […]

Regression of Fibrosis Following Hepatitis C Eradication

G&H Which patients are most likely to experience fibrosis regression following the eradication of hepatitis C? SF One of the many benefits of developing effective, well-tolerated […]