Clinical Guide to Navigating the Landscape of Biosimilars for Inflammatory Bowel Disease

Abstract: Annual out-of-pocket expenditures for patients with inflammatory bowel disease (IBD) are estimated to be as high as $41,000, with medications, such as biologics, being one […]

Family Planning for Patients With Inflammatory Bowel Disease in the Post-Dobbs Era

Abstract: Federal protections for abortion care in the United States ended in June 2022. For people with inflammatory bowel disease (IBD) who are capable of pregnancy, […]

A Clinical Review of Noninvasive Tests for Hepatic Fibrosis

Abstract: Identifying hepatic fibrosis is paramount in managing patients with chronic liver disease. The etiology of liver disease can be owing to many factors, including chronic […]

Is It Time for Noncontinuous Therapy for Gastroesophageal Reflux Disease?

Abstract: Gastroesophageal reflux disease (GERD) is a chronic disorder characterized by the reflux of gastric contents into the esophagus, leading to symptoms and potential long-term complications […]

Leaky Gut Syndrome: Myths and Management

Abstract: Leaky gut syndrome is a condition widely popularized in the lay literature, although it is not currently accepted as a formal medical diagnosis. Multiple gastrointestinal […]

Cardiovascular Comorbidities and Inflammatory Bowel Disease: Causes and Consequences

Abstract: Patients with inflammatory bowel disease (IBD) have an increased risk of cardiovascular disease (CVD) such as myocardial infarction and stroke. CVD in patients with IBD […]

Best Practices for Helicobacter pylori Management

Abstract: For decades, antimicrobial therapy for Helicobacter pylori infection has been given empirically, and the results of therapy (success or failure) have either not been confirmed […]

Update on the Screening, Diagnosis, and Management of Cholangiocarcinoma

Abstract: Cholangiocarcinoma (CCA) is a neoplasm of the biliary tract that has become increasingly prevalent throughout the world. Common risk factors for developing CCA include cirrhosis, […]

A Review of New Concepts in Iron Overload

Abstract: Iron overload disorders are conditions that can lead to increased body iron stores and end-organ damage in affected organs. Increased iron deposition most commonly occurs […]

A Practical Update on COVID-19 and Inflammatory Bowel Disease: COVID-19 Disease Risk and Vaccine Safety and Efficacy

Abstract: The COVID-19 pandemic introduced significant uncertainty regarding the care of patients with inflammatory bowel disease (IBD). Substantial research efforts have made progress in answering many […]

Esophagogastric Junction Outflow Obstruction: A Diagnosis in Evolution

Abstract: Esophagogastric junction outflow obstruction (EGJOO) is a rapidly evolving diagnosis that can represent early or variant achalasia. Since the publication of the Chicago Classification version […]

Depression and the Aberrant Intestinal Microbiome

Abstract: Depression is one of the most common mental health disorders affecting adults in the United States. The current treatment is the combination of pharmacotherapy and […]

Noninvasive Methods for Assessing Liver Fibrosis and Steatosis

Abstract: Accurate diagnosis and staging of liver fibrosis is crucial to the individualized management of patients with chronic liver disease. Liver biopsy remains the reference standard […]

Are All Janus Kinase Inhibitors for Inflammatory Bowel Disease the Same?

Abstract: Ulcerative colitis and Crohn’s disease are chronic, progressive inflammatory bowel diseases (IBDs) and are without a known cure. Janus kinase (JAK) is a family of […]

The Importance of Making an Accurate Diagnosis for Hepatic Encephalopathy

Patient Case A 43-year-old White male with metabolic syndrome presented with complaints of fatigue and feeling distracted. Blood work showed a mild increase in aspartate aminotransferase […]

Recent Approaches in Portal Hypertension Involving Risk Stratification and Medical Management

Abstract: Portal hypertension leads to the formation of portosystemic collaterals that divert portal blood to the systemic circulation and bypass the liver, resulting in multiple severe […]

Hepatitis C Virus Elimination in the United States: Challenges, Progress, and Future Steps

Abstract: Hepatitis C virus (HCV) infection is a major public health challenge with a simple, highly efficacious, all-oral therapy (direct-acting antivirals) that can achieve cure. Owing […]

Dietary Management of Eosinophilic Esophagitis

Abstract: Eosinophilic esophagitis (EoE) is a chronic immune-mediated food antigen–driven disease characterized by tissue eosinophilia and clinical symptoms of esophageal dysfunction. Medical and dietary therapies can […]

Management Considerations for the Older Adult With Inflammatory Bowel Disease

Abstract: As the prevalence of older adults with inflammatory bowel disease (IBD) is rising, understanding the unique challenges in both diagnosis and management is becoming increasingly […]

New Developments in Bile Acid Diarrhea

Abstract: Bile acid diarrhea (BAD) is characterized by increased frequency of bowel movements, looser stool consistency, urgency, and need for proximity to toilet facilities owing to […]