A Review of New Concepts in Iron Overload

Abstract: Iron overload disorders are conditions that can lead to increased body iron stores and end-organ damage in affected organs. Increased iron deposition most commonly occurs […]

A Practical Update on COVID-19 and Inflammatory Bowel Disease: COVID-19 Disease Risk and Vaccine Safety and Efficacy

Abstract: The COVID-19 pandemic introduced significant uncertainty regarding the care of patients with inflammatory bowel disease (IBD). Substantial research efforts have made progress in answering many […]

Esophagogastric Junction Outflow Obstruction: A Diagnosis in Evolution

Abstract: Esophagogastric junction outflow obstruction (EGJOO) is a rapidly evolving diagnosis that can represent early or variant achalasia. Since the publication of the Chicago Classification version […]

Depression and the Aberrant Intestinal Microbiome

Abstract: Depression is one of the most common mental health disorders affecting adults in the United States. The current treatment is the combination of pharmacotherapy and […]

Noninvasive Methods for Assessing Liver Fibrosis and Steatosis

Abstract: Accurate diagnosis and staging of liver fibrosis is crucial to the individualized management of patients with chronic liver disease. Liver biopsy remains the reference standard […]

Are All Janus Kinase Inhibitors for Inflammatory Bowel Disease the Same?

Abstract: Ulcerative colitis and Crohn’s disease are chronic, progressive inflammatory bowel diseases (IBDs) and are without a known cure. Janus kinase (JAK) is a family of […]

The Importance of Making an Accurate Diagnosis for Hepatic Encephalopathy

Patient Case A 43-year-old White male with metabolic syndrome presented with complaints of fatigue and feeling distracted. Blood work showed a mild increase in aspartate aminotransferase […]

Recent Approaches in Portal Hypertension Involving Risk Stratification and Medical Management 

Abstract: Portal hypertension leads to the formation of portosystemic collaterals that divert portal blood to the systemic circulation and bypass the liver, resulting in multiple severe […]

Hepatitis C Virus Elimination in the United States: Challenges, Progress, and Future Steps 

Abstract: Hepatitis C virus (HCV) infection is a major public health challenge with a simple, highly efficacious, all-oral therapy (direct-acting antivirals) that can achieve cure. Owing […]

Dietary Management of Eosinophilic Esophagitis

Abstract: Eosinophilic esophagitis (EoE) is a chronic immune-mediated food antigen–driven disease characterized by tissue eosinophilia and clinical symptoms of esophageal dysfunction. Medical and dietary therapies can […]

Management Considerations for the Older Adult With Inflammatory Bowel Disease

Abstract: As the prevalence of older adults with inflammatory bowel disease (IBD) is rising, understanding the unique challenges in both diagnosis and management is becoming increasingly […]

New Developments in Bile Acid Diarrhea

Abstract: Bile acid diarrhea (BAD) is characterized by increased frequency of bowel movements, looser stool consistency, urgency, and need for proximity to toilet facilities owing to […]

Improving the Management of Hepatorenal Syndrome–Acute Kidney Injury Using an Updated Guidance and a New Treatment Paradigm

Abstract: Cirrhosis, or advanced scarring of the liver, represents the end stage of chronic liver disease and is associated with high morbidity and mortality. Hepatorenal syndrome–acute […]

Current and Novel Uses of Intestinal Ultrasound in Inflammatory Bowel Disease

Abstract: Intestinal ultrasound (IUS) is a patient-centric, noninvasive, real-time, point-of-care tool with the capability to aid in diagnosis and monitoring of disease activity in both Crohn’s […]

A New Tool to Assess Disease Severity in Eosinophilic Esophagitis

Abstract: The presentation of eosinophilic esophagitis (EoE) is heterogeneous with varied clinical, endoscopic, and histologic features impacting the severity of the condition. Until recently, however, and […]

Leveraging Virtual Technology to Conduct Clinical Trials in Inflammatory Bowel Disease

Abstract: Clinical trials have led to major advances in inflammatory bowel disease (IBD) care over the last few decades, yet in that time most clinical trial […]

Update on Clinical Trials for Nonalcoholic Steatohepatitis

Abstract: Tremendous effort has been put forth over the past 2 decades in understanding the pathophysiology of nonalcoholic fatty liver disease/nonalcoholic steatohepatitis (NAFLD/NASH). Although multiple potential […]

New Techniques to Screen for Barrett Esophagus

Abstract: Barrett esophagus (BE) is the only known precursor to esophageal adenocarcinoma (EAC), a cancer that continues to have a poor 5-year survival rate of 20%. […]

Understanding the Current Approaches in the Management of IBS-C: A Case Study

Patient Case A 36-year-old woman presents with persistent abdominal pain and constipation (Table 1). Upon inquiry, she states that she has experienced abdominal and bowel-related symptoms […]

Clostridioides difficile Infection: Landscape and Microbiome Therapeutics 

Abstract: Clostridioides difficile infection (CDI) is the leading cause of hospital-acquired diarrhea and is common in the community. Both younger individuals who may be healthy otherwise […]

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