Durvalumab Plus Tremelimumab for First-Line Treatment of Hepatocellular Carcinoma

G&H What is the rationale for using durvalumab and tremelimumab in combination for the treatment of hepatocellular carcinoma? RK Durvalumab (Imfinzi, AstraZeneca) and tremelimumab (Imjudo, AstraZeneca) […]

Current Status of Hepatocellular Carcinoma Surveillance

G&H  What evidence is currently available showing the benefits of hepatocellular carcinoma surveillance?  NP  The benefits of hepatocellular carcinoma (HCC) surveillance have been evaluated in several […]

Selective Internal Radiation Therapy Using Yttrium-90 in Early and Intermediate Hepatocellular Carcinoma

G&H  How does selective internal radiation therapy using yttrium-90 work? RS  Selective internal radiation therapy (SIRT), also known as radioembolization, involves the intra-arterial injection of micron-sized […]

Hepatocellular Carcinoma and Hepatitis Delta Virus

G&H  Is hepatitis delta virus oncogenic? NR  The simple answer is yes, although hepatitis delta virus (HDV) is not yet labeled as a carcinogenic virus. It […]

Detection of Early-Stage Hepatocellular Carcinoma Using Abbreviated Magnetic Resonance Imaging

G&H How does abbreviated magnetic resonance imaging differ from conventional magnetic resonance imaging? NP Several protocols exist for abbreviated magnetic resonance imaging (MRI), but in general […]

The Evolving Role of Combination Systemic Therapies in Hepatocellular Carcinoma

G&H  What are the treatment goals in hepatocellular carcinoma? RK In hepatocellular carcinoma (HCC), the treatment goals depend on the stage of the cancer. For early-stage […]

The Use of Albumin-Bilirubin Grade in Patients With Hepatocellular Carcinoma

G&H  How and why did albumin-bilirubin grade come to be used in patients with hepatocellular carcinoma?  PG  Over a decade ago, the SHARP trial demonstrated the […]

Exploring the Potential Chemoprophylactic Role of Carvedilol for Hepatocellular Carcinoma

G&H  What are the notable risk factors for hepatocellular carcinoma? RS  The main risk factor for hepatocellular carcinoma (HCC) is liver cirrhosis. A damaged liver with […]

The Role of Liver Biopsy in Hepatocellular Carcinoma

Gastroenterology & Hepatology October 2016, Volume 12, Issue 10 Richard S. Finn, MD Associate Professor of Medicine Department of Medicine Division of Hematology/Oncology Geffen School of […]

Sorafenib in Combination With Transarterial Chemoembolization for the Treatment of Hepatocellular Carcinoma

Gastroenterology & Hepatology Volume 12, Issue 8, August 2016 Jean-Francois H. Geschwind, MD Chairman, Department of Radiology and Biomedical Imaging Professor of Radiology and Oncology Yale […]

Surveillance for Hepatocellular Carcinoma

Gastroenterology & Hepatology Volume 12, Issue 6, June 2016 Catherine Frenette, MD Medical Director of Liver Transplantation Scripps Center for Organ Transplantation La Jolla, California G&H […]

The Relationship Between Hepatocellular Carcinoma and Hepatitis B and C Virus

Gastroenterology & Hepatology February 2016, Volume 12, Issue 2 Anita Kohli, MD, MS Infectious Disease Physician/Scientist Chair of Research, Department of Medicine Director of Research, Department […]

The Use of Genetic Alterations in the Development of Liver Cancer Drugs

Gastroenterology & Hepatology December 2015, Volume 11, Issue 12 Ghassan K. Abou-Alfa, MD Associate Professor Gastrointestinal Oncology Service Memorial Sloan Kettering Cancer Center Weill Cornell Medical […]

Locoregional Therapy for Patients With Hepatocellular Carcinoma

Gastroenterology & Hepatology October 2015, Volume 11, Issue 10 Jean-Francois H. Geschwind, MD Professor of Radiology and Oncology Chairman, Department of Diagnostic Radiology Yale School of […]

Treatment of Intermediate-Stage Hepatocellular Carcinoma

Gastroenterology & Hepatology August 2015, Volume 11, Issue 8   Richard S. Finn, MD Associate Professor of Medicine Department of Medicine, Division of Hematology/Oncology Geffen School […]

Imaging Techniques for Hepatocellular Carcinoma

Claude Sirlin, MD Professor of Radiology University of California, San Diego San Diego, California G&H Is there a standardized protocol for the use of ultrasound in […]

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