Early Intervention in Crohn’s Disease

G&H  What biologic features of Crohn’s disease support the rationale for early intervention? BS Crohn’s disease is a chronic, progressive, transmural inflammatory disease in which ongoing […]

Differences in Inflammatory Bowel Disease Across Ethnicities and Racial Groups

G&H  What is the prevalence of inflammatory bowel disease across ethnicities and racial groups in the United States? OD  Data from the National Health Interview Survey […]

JAK Inhibitor–Associated Acne in IBD: Recognition and Management

G&H  How often does acne develop in inflammatory bowel disease patients treated with Janus kinase inhibitors? BC  Acne is most commonly associated with the Janus kinase […]

When Should Pediatric Inflammatory Bowel Disease Patients Be Allowed to Take Approved Therapies for Adults?

G&H  If an inflammatory bowel disease therapy works for adults, can it be extrapolated that the therapy may also work for adolescents and children? MK  Extrapolation […]

Mitigating the Adverse Effects of Poor Nutritional Status in the Management of Adult Patients With Crohn’s Disease

G&H  How much impact do poor nutritional status and inadequate nutrition therapy have on adult patients with Crohn’s disease? SM  Malnutrition has an adverse effect on […]

Inflammatory Bowel Disease and Eosinophilic Esophagitis

G&H  Do patients with inflammatory bowel disease have a higher risk of eosinophilic esophagitis?  EB  Several single-center studies have shown that patients with inflammatory bowel disease […]

Pouch Surveillance: The Bottom Line

G&H  What are the arguments for and against pouch surveillance? SH  First of all, it should be kept in mind that although total proctocolectomy with ileoanal […]

Insights Into Colonoscopic Surveillance for Dysplasia in Inflammatory Bowel Disease

G&H  How has colonoscopic imaging evolved? JL  The major change that has occurred is improvement in the optics of colonoscopes. Providers used to be accustomed to […]

Anastomoses for Ileocolonic Resection in Patients With Crohn’s Disease

G&H  What are the most common types of anastomoses currently being used for ileocolonic resection in Crohn’s disease? FM  There are currently 4 types of anastomoses. […]

Exploring the Potential of TL1A Inhibition in the Treatment of Inflammatory Bowel Disease Patients 

G&H  How does tumor necrosis factor-like ligand 1A differ from tumor necrosis factor?  ST  In 2002, my colleagues at Cedars-Sinai and I discovered the expression of […]

Prehabilitation for Inflammatory Bowel Disease Surgery

G&H  What is the rationale for prehabilitation for inflammatory bowel disease surgery? JA  Prehabilitation is good for almost any type of surgery, not just inflammatory bowel […]

How to Approach Immune Checkpoint Inhibitor Enterocolitis 

G&H  What are the similarities and differences between immune checkpoint inhibitor enterocolitis and inflammatory bowel disease in terms of etiology, clinical presentation, and endoscopic presentation? YW  […]

Current Status of Fecal Microbiota Transplantation for Inflammatory Bowel Disease Management

G&H  Based on the research to date, does fecal microbiota transplantation show promise for the treatment of ulcerative colitis? JA  Yes, although there is still a […]

Treating Patients With Inflammatory Bowel Disease During and After Cancer

G&H  What is the risk of cancer in patients with inflammatory bowel disease?  JA  Individuals with inflammatory bowel disease (IBD) are at an increased risk of […]

Insights Into Cell Therapies for Patients With Inflammatory Bowel Disease

G&H  Why has there been interest in using cell therapies to treat patients with inflammatory bowel disease? LC  For a long time, it seemed like it […]

What Is Moderate to Severe Inflammatory Bowel Disease?

G&H  Why is it important to define moderate to severe inflammatory bowel disease? LP-B  It is very important to define moderate to severe inflammatory bowel disease […]

Use of Interleukin-23 Inhibitors for the Treatment of Inflammatory Bowel Disease

G&H  Why did interleukin-23 inhibition become a treatment approach for inflammatory bowel disease? EL  There are several reasons. One is that overexpression of interleukin (IL)-23 has […]

Management of Patients With Refractory Ulcerative Proctitis

G&H What is the current understanding of the relationship between ulcerative proctitis and ulcerative colitis? MC Ulcerative proctitis is part of the disease spectrum of ulcerative […]

Use of Glucagon-Like Peptide-1 Receptor Agonists in Patients With Inflammatory Bowel Disease

G&H How prevalent are obesity and overweight in patients with inflammatory bowel disease, and how can these conditions affect this patient population? CB With the global […]

The Potential Role of Hyperbaric Oxygen Therapy in Patients With Inflammatory Bowel Disease

G&H  Why has hyperbaric oxygen therapy been considered for the treatment of patients with inflammatory bowel disease? PD  Inflammatory bowel disease (IBD), which encompasses both Crohn’s […]

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