Treatment De-Escalation in Patients With Inflammatory Bowel Disease

Amanda Israel, MD, Katia El Jurdi, MD, and David T. Rubin, MD

  Abstract: Inflammatory bowel disease follows a relapsing and remitting course that can be augmented with the use of various pharmacologic therapies. Treatments used to induce […]

Thrombocytopenia in Chronic Liver Disease and the Role of Thrombopoietin Agonists

Jennifer B. Miller, MD, Esteban J. Figueroa, MD, Rebecca M. Haug, MD, and Neeral L. Shah, MD

  Abstract: Thrombocytopenia is a common complication of chronic liver disease and creates clinical challenges for patients who need invasive procedures. Options available to increase platelet […]

Esophageal Dilation as the Primary Treatment for Eosinophilic Esophagitis

David A. Katzka, MD

  G&H  What are the different phenotypes of eosinophilic esophagitis, and how are they typically treated? DK  It is challenging to identify the phenotypes of eosinophilic […]

Update on Pregnancy in Patients With Inflammatory Bowel Disease

Anita Afzali, MD, MPH

  G&H  What is the current understanding of the relationship between inflammatory bowel disease and fertility? AA  Female patients whose inflammatory bowel disease (IBD) is under […]

EUS-Guided Gastroenterostomy Vs Duodenal Stenting for the Palliation of Malignant Gastric Outlet Obstruction

Mouen A. Khashab, MD

  G&H  What methods are available to palliate patients with malignant gastric outlet obstruction? MK  Surgical gastrojejunostomy, duodenal stenting, and endoscopic ultrasound (EUS)-guided gastroenterostomy are the […]

Update on the Risk of Primary and Recurrent HCC With the Use of DAA Therapy for HCV Infection

Jordan Feld, MD, MPH

  G&H  What is the current understanding of the relationship between hepatocellular carcinoma and hepatitis C virus infection? JF  Hepatitis C virus (HCV) is a carcinogenic […]

Gastro-Hep News

Samantha Alleman

US Food and Drug Administration Approves Teduglutide for Pediatric Patients With Short Bowel Syndrome On May 17, 2019, the US Food and Drug Administration (FDA) expanded […]

Emerging Research on MGL-3196 for the Treatment of Nonalcoholic Steatohepatitis

Zobair Younossi, MD, MPH

  G&H  What is the mechanism of action of MGL-3196? ZY  MGL-3196 (Madrigal Pharmaceuticals) is a thyroid hormone receptor β agonist. Thyroid hormone receptors can be […]

Letter From the Editor: De-Escalation of Therapy for Inflammatory Bowel Disease

Gary R. Lichtenstein, MD, AGAF, FACP, FACG

When and how should therapy be de-escalated in patients with Crohn’s disease and ulcerative colitis? In this month’s issue of Gastroenterology & Hepatology, Dr Amanda Israel, […]

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