HCC

Current and Future Systemic Therapies for Hepatocellular Carcinoma

Fernand Bteich, MD, and Adrian M. Di Bisceglie, MD

Abstract: Hepatocellular carcinoma (HCC) is a common cancer with unmet needs and limited effective therapeutic options. The management strategy for diagnosed HCC is based on […]

IBD

The Expanding Role of Anti–IL-12 and/or Anti–IL-23 Antibodies in the Treatment of Inflammatory Bowel Disease

Amir Kashani, MD, MPH, and David A. Schwartz, MD

Abstract: The interleukin (IL)-12/IL-23 pathway is one of many proposed mechanistic pathways of intestinal inflammation. Earlier studies introduced IL-12 as a major cytokine in the […]

Cirrhosis

Nutrition in Patients With Cirrhosis

Fernando Calmet, MD, Paul Martin, MD, and Michelle Pearlman, MD

Abstract: Malnutrition is a common complication of cirrhosis, increases in frequency with Child-Turcotte-Pugh (CTP) score, and is associated with an increased morbidity and mortality. Although […]

IBS

Irritable Bowel Syndrome, Disordered Eating, and Eating Disorders

Kimberly N. Harer, MD, ScM

G&H What is the difference between disordered eating and an eating disorder? KH Disordered eating occurs when individuals regularly engage in eating patterns that do not […]

IBD

The Impact of Biologic Therapy on Outcomes of Inflammatory Bowel Disease Surgery

Edward V. Loftus Jr, MD

G&H Has the rate of inflammatory bowel disease surgery changed since biologic agents were introduced? EL The surgical rate has decreased with the advent of biologic […]

Hepatology

Long-Term Use of Azathioprine in the Management of Autoimmune Hepatitis

Marion G. Peters, MBBS, MD, FRACP

6 G&H How effective are the first- and second-line treatment options for autoimmune hepatitis? MP First-line treatment consists of corticosteroids with azathioprine. A number of randomized, […]

Letter From the Editor

Letter From the Editor: Eating Disorders and Disordered Eating Habits in Patients With Irritable Bowel Syndrome

Gary R. Lichtenstein, MD, AGAF, FACP, FACG

How can clinicians identify if the patient they are treating has an eating disorder? This is one of the questions posed in our Advances in […]