Insights on the Risk of Hepatocellular Carcinoma in Patients With Nonalcoholic Steatohepatitis

G&H What is the prevalence of hepatocellular carcinoma in patients with nonalcoholic steatohepatitis? AS Hepatocellular carcinoma (HCC) is the 7th most common cancer worldwide, with approximately […]

Review of Liver Transplantation in Patients With Hepatocellular Carcinoma

G&H Why has there been an increase in liver transplants performed for the indication of hepatocellular carcinoma? FY Hepatocellular carcinoma (HCC) is one of the leading […]

How to Choose Second-Line Treatment for Hepatocellular Carcinoma

G&H What are the current options for first-line medical treatment of hepatocellular carcinoma? CF Recently, there has been a significant progression in the options that are […]

Nivolumab and Ipilimumab Combination Therapy for Second-Line Treatment of Hepatocellular Carcinoma

G&H Could you discuss the evolution of the first- and second-line medical treatment options for hepatocellular carcinoma? FB Hepatocellular carcinoma (HCC) is one of the fastest-growing […]

Update on the Diagnosis and Treatment of Hepatocellular Carcinoma

Abstract: Hepatocellular carcinoma (HCC) is the fourth-leading cause of cancer-related mortality worldwide and the fastest-rising cause of cancer-related death in the United States. Given the […]

Risk of Hepatocellular Carcinoma Using Tenofovir Disoproxil Fumarate Vs Entecavir for Hepatitis B Virus Treatment

G&H What is the current understanding of the relationship between hepatocellular carcinoma and hepatitis B virus infection? RW Patients infected with chronic hepatitis B virus […]

Current Status of the Use of Statins and Aspirin in the Chemoprevention of Hepatocellular Carcinoma

G&H What are the main risk factors for hepatocellular carcinoma? YH Hepatocellular carcinoma (HCC) almost exclusively develops from underlying chronic liver disease, which is characterized […]

Atezolizumab and Bevacizumab Combination Therapy for Hepatocellular Carcinoma

G&H What are the current first-line medical treatment options for hepatocellular carcinoma? AE-K Two drugs have been approved for the first-line treatment of hepatocellular carcinoma […]

Current Status of the GALAD and BALAD Biomarker Models for Hepatocellular Carcinoma

G&H How has the role of biomarkers evolved in hepatocellular carcinoma? LR Perhaps the most common way that biomarkers are being used is to aid […]

Overview of Ablative Therapy for Hepatocellular Carcinoma

G&H What is the role of radiofrequency ablation and microwave ablation in the treatment of hepatocellular carcinoma? SR Both radiofrequency ablation and microwave ablation are […]

Update on the Risk of Primary and Recurrent HCC With the Use of DAA Therapy for HCV Infection

G&H What is the current understanding of the relationship between hepatocellular carcinoma and hepatitis C virus infection? JF Hepatitis C virus (HCV) is a carcinogenic […]

Current and Future Systemic Therapies for Hepatocellular Carcinoma

Abstract: Hepatocellular carcinoma (HCC) is a common cancer with unmet needs and limited effective therapeutic options. The management strategy for diagnosed HCC is based on […]

Statins and Hepatocellular Carcinoma Protection

G&H What have studies found regarding the possible relationship between statins and hepatocellular carcinoma protection? DK Approximately 10 years ago, the first large study looking at […]

The Use of Checkpoint Inhibitors in Patients With Hepatocellular Carcinoma

G&H Why have checkpoint inhibitors been studied in the setting of hepatocellular carcinoma? GAA The liver is an important organ through which toxins and microbial products […]

Treatment of Hepatocellular Carcinoma With Lenvatinib

G&H What is the mechanism of action of lenvatinib? K-HH Lenvatinib (Lenvima, Eisai) is a tyrosine kinase inhibitor selectively targeting vascular endothelial growth factor receptor […]

Drugs in Development for Hepatocellular Carcinoma

G&H What have been the most recent advances or changes in hepatocellular carcinoma drug development? LR For approximately 10 years, the only drug available for […]

Update on HCC Management and Review of the New EASL Guidelines

G&H How and when were the new European guidelines for hepatocellular carcinoma management developed? AA As part of its educational activities, the European Association for […]

Risk of Hepatocellular Carcinoma in Patients With Nonalcoholic Steatohepatitis

G&H How common are nonalcoholic steatohepatitis and hepatocellular carcinoma in the United States, and how often do they coexist in a patient? MC Fatty liver […]

Update on New Drugs and Those in Development for the Treatment of Primary Biliary Cholangitis

Abstract: Primary biliary cholangitis (PBC) is an autoimmune inflammatory liver disease of the interlobular bile ducts that can lead to cirrhosis and liver failure. Until […]

Elastography and the Risk of Hepatocellular Carcinoma

G&H How can elastography be performed? JT The most common way to perform elastography, or measurement of the stiffness of a liver, is by using […]