The Role of Endohepatology in the Management of Liver Disease

G&H  What is encompassed by the term endohepatology? AS  Broadly, the term endohepatology refers to endoscopic and endoscopic ultrasound (EUS)-guided interventions in patients with liver disease. […]

Examining the New Definition of Hepatorenal Syndrome and the Role of Terlipressin

G&H  How common is hepatorenal syndrome, and what are its potential consequences? RB  Hepatorenal syndrome is the most serious complication of cirrhosis and portal hypertension and […]

The Possible Effects of Ursodeoxycholic Acid on Recurrent Primary Biliary Cholangitis and Biliary Complications After Liver Transplant

G&H  What are the effects of ursodeoxycholic acid when used as first-line treatment for primary biliary cholangitis, and how often does adequate response to this treatment […]

Overview of COVID-19 and the Liver

G&H  What are the typical presenting symptoms of COVID-19? How may the liver be involved? DJ  Most patients infected with COVID-19 present with respiratory symptoms, particularly […]

The Evolving Role of Advanced Endoscopic Techniques in Hepatology

Abstract: The role of advanced endoscopy in the field of hepatology has evolved rapidly over the last decade. Several novel diagnostic and therapeutic interventions can now […]

Current Status of Liver Transplantation

G&H  Currently, what are the most common indications for liver transplantation in the United States? RV  The 3 most common indications for liver transplantation in cirrhotic […]

Overview of Current Management of Portal Hypertension

  G&H  Currently, what are the most common causes of portal hypertension? GG-T  Portal hypertension is high pressure in the portal vein, which is the vein […]

Presentations of Wilson Disease

  G&H  What is Wilson disease? MS  Wilson disease is a disorder of copper metabolism that occurs in roughly 1 in 30,000 individuals, although some possibility […]

Liver Transplantation During the COVID-19 Pandemic

  G&H  Are patients awaiting liver transplantation at greater risk of becoming infected with coronavirus disease 2019?  KRR  Patients with advanced liver disease are cited by […]

Hepatic Complications and Liver Transplant in Congenital Cardiac Disease 

G&H  What is the current understanding of the relationship between the liver and the heart? KB  The liver is the hub for several metabolic activities. In […]

Current and Emerging Treatment Options for Primary Biliary Cholangitis 

  G&H  What is the current first-line therapy for primary biliary cholangitis, and what percentage of patients do not respond to it? AB  Currently, the only […]

Update on Liver Transplantation in Patients With Alcoholic Hepatitis

  G&H  How has alcoholic hepatitis traditionally been treated? CO  Alcoholic hepatitis has traditionally been treated with thiamine, folic acid, and multivitamins and by increasing the […]

Best Use of the Transjugular Intrahepatic Portosystemic Shunt Procedure for the Management of Portal Hypertension

G&H  What are the traditional treatments for portal hypertension, and how effective are they? LVW  Cirrhosis is a major cause of portal hypertension, which has consequences […]

Idiopathic Noncirrhotic Portal Hypertension

  G&H  What is noncirrhotic portal hypertension, and what are the most common causes of this condition? HJ  Noncirrhotic portal hypertension is an increased pressure gradient […]

Emerging Research on MGL-3196 for the Treatment of Nonalcoholic Steatohepatitis

  G&H  What is the mechanism of action of MGL-3196? ZY  MGL-3196 (Madrigal Pharmaceuticals) is a thyroid hormone receptor β agonist. Thyroid hormone receptors can be […]

Long-Term Use of Azathioprine in the Management of Autoimmune Hepatitis

6 G&H  How effective are the first- and second-line treatment options for autoimmune hepatitis? MP  First-line treatment consists of corticosteroids with azathioprine. A number of randomized, […]

Current Management of Thrombocytopenia in Chronic Liver Disease

  G&H  How common is thrombocytopenia in patients who have chronic liver disease? RB  Thrombocytopenia, defined as a platelet count under 150,000/µL, is probably the most […]

Treatment of Portopulmonary Hypertension With Macitentan in Patients With Cirrhosis

  G&H  What is the current understanding of the relationship between pulmonary hypertension and cirrhosis? MK  Any liver disease or vascular problem in the liver can […]

Drug-Induced Liver Injury

  G&H  What are the different types of drug-induced liver injury? NC  Drug-induced liver injury can be divided into direct hepatotoxicity and idiosyncratic drug-induced liver injury. […]

Use of Obeticholic Acid in Patients With Primary Biliary Cholangitis

  G&H  Why was there a need for a treatment option in addition to ursodeoxycholic acid for patients with primary biliary cholangitis? RB  Many primary biliary […]

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