Missing the Mark: Optimizing Endoscopy for Intestinal Metaplasia and Gastric Cancer Detection in the United States

G&H What is the risk of gastric cancer relative to that of colorectal cancer worldwide and in the United States? JHH Colorectal cancer, broadly speaking, affects […]

Potential Use of Artificial Intelligence in the Histologic Assessment of Nonalcoholic Steatohepatitis

G&H Where may there be a potential role for the use of artificial intelligence in the histologic assessment of nonalcoholic steatohepatitis? QA When using histology to […]

Emerging Treatments for Patients With Nonalcoholic Steatohepatitis

G&H What have been the challenges of drug development in nonalcoholic steatohepatitis? VR One challenge has been that drug trials need to be very long because […]

Recent Research and Insights on the Disease Burden of Nonalcoholic Fatty Liver Disease and Nonalcoholic Steatohepatitis

G&H How has the prevalence of nonalcoholic fatty liver disease and nonalcoholic steatohepatitis changed? ZY The prevalence of both nonalcoholic fatty liver disease (NAFLD) and nonalcoholic […]

Lifestyle Modifications for Patients With Nonalcoholic Steatohepatitis

G&H What is the role of diet and exercise in the treatment of patients with nonalcoholic steatohepatitis? SZ-S Nonalcoholic steatohepatitis (NASH) is mainly a lifestyle-oriented disease, […]

The Relationship Between Nonalcoholic Fatty Liver Disease and Chronic Kidney Disease

G&H Has research demonstrated that there is an association between nonalcoholic fatty liver disease, including nonalcoholic steatohepatitis, and chronic kidney disease? CB Before answering this question, […]

Alcohol Consumption and Nonalcoholic Steatohepatitis/Nonalcoholic Fatty Liver Disease

G&H Are there notable differences between alcohol-related liver disease and nonalcoholic steatohepatitis/nonalcoholic fatty liver disease other than the consumption of alcohol? ML Histologically, alcohol-related liver disease […]

The Gut Microbiome and Nonalcoholic Steatohepatitis

G&H What makes up a healthy microbiome? JS A healthy microbiome is not completely identical in every person. It is influenced by the type of diet, […]

Drug Development for the Management of Nonalcoholic Steatohepatitis Cirrhosis

G&H What is the prevalence of cirrhosis in patients who have nonalcoholic steatohepatitis? NA Cirrhosis, or stage 4 fibrosis, is the last stage of the histologic […]

Magnetic Resonance Elastography as a Predictor of Response to Therapy in Patients With Nonalcoholic Steatohepatitis

G&H How is response to therapy defined in patients with nonalcoholic steatohepatitis? MN Approximately 5 years ago, experts, regulators, and governing societies sought to determine the […]

Lean Nonalcoholic Steatohepatitis and Nonalcoholic Fatty Liver Disease

G&H Is lean nonalcoholic steatohepatitis on the spectrum of nonalcoholic fatty liver disease or a novel entity? NG Lean nonalcoholic steatohepatitis (NASH) is on the spectrum […]

Genetics of Nonalcoholic Steatohepatitis

G&H What are the main genes involved with nonalcoholic steatohepatitis? AS There are a growing number of genes that have been linked both to the […]

Current Understanding of Risk for Nonalcoholic Steatohepatitis and Progressive Fibrosis

G&H What is the natural history of nonalcoholic steatohepatitis? MN Nonalcoholic steatohepatitis (NASH) is part of the disease spectrum of nonalcoholic fatty liver disease (NAFLD). […]

The Future of Treatment for Nonalcoholic Steatohepatitis

G&H How has nonalcoholic steatohepatitis traditionally been treated? MC No therapies have yet been approved by the US Food and Drug Administration (FDA) for the […]

Role of Noninvasive Biomarkers in the Diagnosis of Nonalcoholic Steatohepatitis With Stage 2 or 3 Fibrosis

G&H Why is the stage of fibrosis important in nonalcoholic steatohepatitis? RL Patients with nonalcoholic fatty liver disease (NAFLD) can be divided into 2 broad […]