Beyond Proton Pump Inhibitors and Nissen Fundoplication: Minimally Invasive Alternatives for Gastroesophageal Reflux Disease

G&H What is the primary cause of gastroesophageal reflux disease, and how common is this condition? RB The primary cause of gastroesophageal reflux disease (GERD) is […]

Diagnosis and Management of Refractory Gastroesophageal Reflux Disease

Abstract: In up to half of patients with symptoms suspected to stem from gastroesophageal reflux disease (GERD), these symptoms persist despite treatment with daily proton pump […]

Update on the Use of Transoral Incisionless Fundoplication for the Treatment of Gastroesophageal Reflux Disease

G&H What options are available for patients with chronic or treatment-refractory gastroesophageal reflux disease? PB This is a complicated question. Medicine is known to work quite […]

Insights on the Potential Use of Potassium-Competitive Acid Blockers in Erosive Esophagitis

G&H How do potassium-competitive acid blockers compare with traditional proton pump inhibitors in terms of mechanism of action? CH Potassium-competitive acid blockers (P-CABs) inhibit the proton […]

Reflux After Peroral Endoscopic Myotomy

G&H What are the main indications for peroral endoscopic myotomy? MK Peroral endoscopic myotomy (POEM) is typically performed for patients with achalasia, and the procedure […]

Treatment of Refractory Gastroesophageal Reflux Disease

Abstract: Gastroesophageal reflux disease (GERD) is a common disorder that is treated with lifestyle modification, weight loss, and medications, such as proton pump inhibitors (PPIs). […]

The Spectrum of Reflux Phenotypes

Abstract: The focus on a symptom-based definition for gastroesophageal reflux disease (GERD) in adults and children has contributed to widespread use of acid suppression medications […]

Endoscopic Approaches for the Treatment of Gastroesophageal Reflux Disease

G&H When should endoscopic therapy, rather than surgical therapy, be considered for the treatment of gastroesophageal reflux disease? RF Endoscopic therapy for the treatment of […]

The Role of Endoscopic Ultrasound in Esophageal Cancer

G&H How common is esophageal cancer, and what are the main risk factors? DF Esophageal cancer is not very common. Approximately 18,000 cases are diagnosed […]

The Role of High-Resolution Manometry in Gastroesophageal Reflux Disease

G&H What is high-resolution manometry primarily used for? What is its role with gastroesophageal reflux disease? CPG High-resolution manometry (HRM) is primarily used for the […]

Update on Endoscopic Approaches for the Management of Gastroesophageal Reflux Disease

Abstract: Gastroesophageal reflux disease (GERD) is one of the most commonly encountered gastrointestinal diseases in outpatient clinics. Proton pump inhibitors (PPIs) are the cornerstone of […]

Simulators in Training for Upper Gastrointestinal Endoscopy

G&H How has endoscopic training evolved over the years? KW The method used to teach endoscopy has changed very little over the years. Training occurs […]

Gastroesophageal Reflux Disease and Eosinophilic Esophagitis

G&H Can you summarize the evolution of gastroesophageal reflux disease and eosinophilic esophagitis as 2 distinct disorders? SS Since the 1980s, it has been well […]

Spectroscopy for Esophageal Diseases

G&H What is the role of spectroscopy in relation to esophageal diseases? JVD Spectroscopy is a powerful diagnostic tool that exploits properties of light beyond […]

Laryngopharyngeal Reflux and Functional Laryngeal Disorder: Perspective and Common Practice of the General Gastroenterologist

Abstract: Laryngopharyngeal reflux (LPR) is an extraesophageal variant of gastroesophageal reflux disease that is associated with chronic cough, hoarseness, dysphonia, recurrent throat clearing, and globus […]

Management of Refractory Benign Esophageal Strictures

G&H What are the most common causes of esophageal strictures? PS A variety of disorders can cause esophageal strictures, including both malignant and benign etiologies. […]

Narrow-Band Imaging for Diagnosing Gastroesophageal Reflux Disease

G&H How are patients with gastroesophageal reflux disease typically diagnosed? NR A diagnosis of gastroesophageal reflux disease (GERD) is typically made based on symptoms. Patients […]

Hybrid Argon Plasma Coagulation in Patients With Barrett Esophagus

G&H What are the most common risk factors for Barrett esophagus? OP The most common risk factors for Barrett esophagus are chronic heartburn and gastroesophageal […]

Acetic Acid Chromoendoscopy in the Setting of Neoplastic Barrett Esophagus

G&H What are the established surveillance protocols for Barrett esophagus? PB The surveillance protocols for Barrett esophagus vary between countries. In general, the American Gastroenterological […]

An Overview of Dietary Therapies for the Treatment of Eosinophilic Esophagitis

G&H What is the connection between food and eosinophilic esophagitis? IH The connection between food and eosinophilic esophagitis (EoE) was first described in a 1995 […]