New Developments in Bile Acid Diarrhea

Abstract: Bile acid diarrhea (BAD) is characterized by increased frequency of bowel movements, looser stool consistency, urgency, and need for proximity to toilet facilities owing to […]

Improving the Management of Hepatorenal Syndrome–Acute Kidney Injury Using an Updated Guidance and a New Treatment Paradigm

Abstract: Cirrhosis, or advanced scarring of the liver, represents the end stage of chronic liver disease and is associated with high morbidity and mortality. Hepatorenal syndrome–acute […]

Current and Novel Uses of Intestinal Ultrasound in Inflammatory Bowel Disease

Abstract: Intestinal ultrasound (IUS) is a patient-centric, noninvasive, real-time, point-of-care tool with the capability to aid in diagnosis and monitoring of disease activity in both Crohn’s […]

A New Tool to Assess Disease Severity in Eosinophilic Esophagitis

Abstract: The presentation of eosinophilic esophagitis (EoE) is heterogeneous with varied clinical, endoscopic, and histologic features impacting the severity of the condition. Until recently, however, and […]

Leveraging Virtual Technology to Conduct Clinical Trials in Inflammatory Bowel Disease

Abstract: Clinical trials have led to major advances in inflammatory bowel disease (IBD) care over the last few decades, yet in that time most clinical trial […]

Update on Clinical Trials for Nonalcoholic Steatohepatitis

Abstract: Tremendous effort has been put forth over the past 2 decades in understanding the pathophysiology of nonalcoholic fatty liver disease/nonalcoholic steatohepatitis (NAFLD/NASH). Although multiple potential […]

New Techniques to Screen for Barrett Esophagus

Abstract: Barrett esophagus (BE) is the only known precursor to esophageal adenocarcinoma (EAC), a cancer that continues to have a poor 5-year survival rate of 20%. […]

Understanding the Current Approaches in the Management of IBS-C: A Case Study

Patient Case A 36-year-old woman presents with persistent abdominal pain and constipation (Table 1). Upon inquiry, she states that she has experienced abdominal and bowel-related symptoms […]

Clostridioides difficile Infection: Landscape and Microbiome Therapeutics

Abstract: Clostridioides difficile infection (CDI) is the leading cause of hospital-acquired diarrhea and is common in the community. Both younger individuals who may be healthy otherwise […]

The Rise of Private Equity in Gastroenterology Practices

Abstract: Private equity (PE) investment in gastroenterology practices has significantly increased over the past several years. Because PE firms are prevented legally from owning a medical […]

Advanced Combination Treatment With Biologic Agents and Novel Small Molecule Drugs for Inflammatory Bowel Disease

Abstract: The use of combination therapy with a biologic agent and immunosuppressant has well-established efficacy and safety and is common practice in the management of inflammatory […]

Botulinum Toxin A Use in the Gastrointestinal Tract: A Reappraisal After Three Decades

Abstract: The discovery of botulinum toxin A (BTX)’s therapeutic properties has led to studies evaluating its usefulness in multiple medical disorders. Its use in the gastrointestinal […]

A Clinical Review of Mesenteric Panniculitis

Abstract: Mesenteric panniculitis (MP) is a benign condition characterized by chronic inflammation and fibrosis of adipose tissue mainly of the small bowel mesentery. MP is commonly […]

The Arrival of Intestinal Ultrasound for Inflammatory Bowel Disease Care in the United States

Abstract: Intestinal ultrasound (IUS) is a noninvasive and highly reliable point-of-care tool to evaluate inflammation of the bowel. It offers comparable accuracy to endoscopy and magnetic […]

Pros and Cons of Breath Testing for Small Intestinal Bacterial Overgrowth and Intestinal Methanogen Overgrowth

Abstract: Breath testing is the most widely utilized modality to diagnose small intestinal bacterial overgrowth (SIBO) and/or intestinal methanogen overgrowth (IMO). Although SIBO can be diagnosed […]

Why Studying Urgency Is Urgent

Abstract: Bowel urgency, the sudden and immediate need to have a bowel movement, is one of the most widely reported and debilitating symptoms of ulcerative colitis. […]

Virtual Reality: A New Treatment Paradigm for Disorders of Gut-Brain Interaction?

Abstract: Disorders of gut-brain interaction (DGBIs), previously called functional bowel disorders, are prevalent, reduce patients’ quality of life, and impose a significant negative economic impact on […]

Management and Risks Before, During, and After Liver Transplant in Individuals With Obesity

Abstract: Obesity has become a global epidemic, adding to the burden of chronic diseases and disabilities. Metabolic syndrome, especially obesity, is a significant risk factor for […]

Fecal Incontinence and Defecatory Disorders in Patients With Ileal Pouch–Anal Anastomosis

Abstract: Functional anorectal disorders are common in patients with ileal pouch–anal anastomosis (IPAA) and often have a debilitating impact on quality of life. The diagnosis of […]

Potassium-Competitive Acid Blockers: Present and Potential Utility in the Armamentarium for Acid Peptic Disorders

Abstract: Potassium-competitive acid blockers (P-CABs) such as vonoprazan represent a novel class of acid suppressants that show tremendous promise to enhance care of acid peptic disorders. […]