Reflecting on a Decade of Sofosbuvir Use for Hepatitis C Virus Treatment

G&H Sofosbuvir was approved with ribavirin or pegylated interferon plus ribavirin just over 10 years ago for the treatment of hepatitis C virus infection. Thinking back […]

Highlights From the ACG Guidelines for Acute Liver Failure

G&H Why were guidelines recently released for acute liver failure? AS The previous North American guidelines on acute liver failure had been released over a decade […]

Preventative Hepatology and the Reduction of All-Cause Mortality in Liver Disease

G&H Why is preventative hepatology important and a growing area of study and interest? JP Preventative hepatology is important because so much of chronic liver disease […]

Delta Hepatitis in the United States: Epidemiology, Testing, and Linkage to Care

G&H What is the current prevalence of delta hepatitis in the United States and worldwide? RG Delta hepatitis, also known as hepatitis delta virus (HDV), requires […]

Social Media and Hepatology

G&H Why should hepatologists and physicians in general engage in social media at all? JW There are many reasons to engage in social media as a […]

Pain Management in Liver Disease

G&H How prevalent are acute and chronic pain in patients with liver disease, and what are the most common sources of pain in this setting? JH […]

Examining the New Definition of Hepatorenal Syndrome and the Role of Terlipressin

G&H How common is hepatorenal syndrome, and what are its potential consequences? RB Hepatorenal syndrome is the most serious complication of cirrhosis and portal hypertension and […]

Pregnancy and Hepatitis C Virus

G&H What is the prevalence of hepatitis C virus in pregnant women, and why has it been increasing recently in the United States? TK A number […]

Screening for Cholangiocarcinoma in Patients With Primary Sclerosing Cholangitis

G&H What is the risk of developing cholangiocarcinoma in patients with primary sclerosing cholangitis? JL Primary sclerosing cholangitis (PSC) is a rare chronic autoimmune and cholestatic […]

Overview of Liver Involvement in Patients With Erythropoietic Protoporphyria

G&H How does erythropoietic protoporphyria differ from other porphyrias, and what are its most common signs and symptoms? CL Erythropoietic protoporphyria (EPP) is a rare genetic […]

Use of Angiotensin-Converting Enzyme Inhibitors in Patients With Liver Disease

G&H How do angiotensin-converting enzyme inhibitors work, and can they have an effect on liver disease? ET Angiotensin-converting enzyme (ACE) inhibitors block an enzyme that increases […]

Gamma-Glutamyl Transferase in Patients With Primary Biliary Cholangitis

G&H What are the possible causes for elevations of gamma-glutamyl transferase? AG Although many factors can cause elevations of gamma-glutamyl transferase (GGT), this enzyme is mainly […]

Regression of Fibrosis Following Hepatitis C Eradication

G&H Which patients are most likely to experience fibrosis regression following the eradication of hepatitis C? SF One of the many benefits of developing effective, well-tolerated […]

Gaps in Hepatitis B Evaluation and Treatment

G&H What is the typical evaluation process for hepatitis B? CC At the first clinic visit, the provider will confirm the diagnosis of hepatitis B and […]

Herbal Drug–Induced Liver Injury

G&H What percentage of cases of liver injury are caused by herbs or herbal drugs? MT Several registries around the world record cases of drug-induced liver […]

Eliminating Hepatitis C Virus Infection in Indigent Patients

G&H What is the current goal for eliminating hepatitis C virus, and how close is the United States to achieving it? ET The World Health Organization […]

Screening for Hepatitis B Virus and Tuberculosis

G&H Currently, how common is coinfection of hepatitis B virus and tuberculosis (active or latent) in the United States? AC It is challenging to assess estimates […]

Insights Into Pig Liver Xenotransplantation

G&H Currently, how large is the shortage of human livers for transplantation in the United States? RM There are currently more than 11,000 patients on the […]

Using Immunomodulatory and Antiviral Strategies in the Quest to Cure Hepatitis B Virus Infection

G&H What should be the endpoint of hepatitis B virus treatment? AG This is an important question. Several meetings were convened by the European Association for […]

Use of Transient Elastography in Children

G&H How does transient elastography work, and how does it compare with liver biopsy for the assessment of fibrosis in children? TM Transient elastography is a […]