Glucagon-Like Peptide-1 Receptor Agonists and Cirrhosis

G&H What is the impact of glucagon-like peptide-1 receptor agonists on the risk of progression to cirrhosis or decompensation? SJ The hallmark ESSENCE trial showed that […]

Current and Emerging Approaches for Management of Primary Sclerosing Cholangitis

G&H How are patients with primary sclerosing cholangitis typically managed currently? KK There is no approved medical therapy for primary sclerosing cholangitis (PSC), so we are […]

Highlights From the Recent AASLD AST Practice Guideline on Adult Liver Transplantation and Graft-Related Complications

G&H Why was there a need to develop this recent practice guideline on adult liver transplantation? EV Liver transplantation is a critical aspect of liver disease […]

Diagnosis and Management of Portal Vein Thrombosis in Patients With Cirrhosis

G&H Is there any need for portal vein thrombosis screening in patients with compensated cirrhosis who do not have any symptoms? JL This is a very […]

Examining the Recent AASLD/IDSA Guidance Test-and-Treat Algorithm Using Point-of-Care HCV RNA Testing

G&H What are the main challenges of current hepatitis C virus treatment? AA The biggest challenge of hepatitis C virus (HCV) treatment is not the treatment […]

Insights Into Liver Transplant Disparities

G&H What liver transplant disparities have been seen in terms of sex? VL When thinking about disparities in liver transplant, it is important to consider disease […]

Management of Patients With Refractory Ascites

G&H What are the typical first steps of management for ascites? SA Ascites, or the buildup of fluid in the abdominal cavity, is related to liver […]

Prophylaxis for Spontaneous Bacterial Peritonitis

G&H What is spontaneous bacterial peritonitis, and what are its potential consequences? RS Spontaneous bacterial peritonitis (SBP) is defined as an infection of ascitic fluid without […]

Update on the Management of Cholestatic Pruritus

G&H Why is cholestatic pruritus important, and how can it affect patients? KB Cholestatic pruritus, or itch, is important because it affects the majority of patients […]

Azathioprine or Mycophenolate Mofetil: Which Should Be Used in Patients With Autoimmune Hepatitis?

G&H How effective and safe is the use of azathioprine in patients with autoimmune hepatitis? AB Autoimmune hepatitis is a chronic inflammatory liver disorder characterized by […]

Can One Plant-Based Meal a Day Help Patients With Hepatic Encephalopathy?

G&H What are the nutritional needs of patients with hepatic encephalopathy? JB The nutritional needs of patients with hepatic encephalopathy (HE) are very complicated because these […]

Highlights From the Recent World Health Organization Guidelines for Hepatitis B Virus Infection

G&H How much progress has been made, particularly in the United States, toward achieving the World Health Organization goal of global hepatitis B elimination by 2030? […]

Management of Suboptimal Response in Primary Biliary Cholangitis Treatment

G&H Currently, what are the main treatment goals for primary biliary cholangitis? GH The goals of primary biliary cholangitis (PBC) treatment are evolving and becoming more […]

Management of Gastric Varices Using Retrograde Transvenous Obliteration Procedures

G&H When should retrograde transvenous obliteration be considered in the management of gastric varices? EL Gastric varices are the second most common type of varices in […]

Highlights From the Recent AASLD Practice Guidelines on Noninvasive Assessment of Hepatic Fibrosis and Steatosis

G&H Why were guidelines recently released on noninvasive assessment of hepatic fibrosis and steatosis, and how were they developed? RS Understanding the fibrosis stage is paramount […]

Overview of Pruritus Management in Patients With Chronic Liver Disease

G&H How common is pruritus in patients with chronic liver disease? AB Overall, the incidence of pruritus or itching in patients with chronic liver disease has […]

Current Management of Patients With Alcohol-Associated Hepatitis

G&H How has alcohol use changed since the COVID-19 pandemic? BL Heavy alcohol use had been declining before the COVID-19 pandemic. The pandemic saw a significant […]

Update on Transjugular Intrahepatic Portosystemic Shunt Use in Liver Disease

G&H Which patients should be considered for early use of a transjugular intrahepatic portosystemic shunt? JB There has been some movement away from previous practice approximately […]

Perioperative Risk in Patients With Cirrhosis

G&H Why do patients with cirrhosis have an increased risk of perioperative morbidity and mortality? KJ Patients with cirrhosis typically have hepatocellular dysfunction and portal hypertension, […]

Frailty, Sarcopenia, and Nutrition in Patients With Cirrhosis

G&H Why is it important to identify frailty and sarcopenia in patients with cirrhosis? JL Frailty and sarcopenia are unfortunately prevalent in patients with cirrhosis. Up […]