Management of Patients With Refractory Ulcerative Proctitis

G&H What is the current understanding of the relationship between ulcerative proctitis and ulcerative colitis? MC Ulcerative proctitis is part of the disease spectrum of ulcerative […]

Nonalcoholic Fatty Liver Disease in Children

Abstract: Nonalcoholic fatty liver disease (NAFLD) is the most common chronic liver disease worldwide. It represents a spectrum of disease from simple hepatic steatosis to steatohepatitis […]

Update on the Role of the Gut Microbiota on Alcohol-Associated Liver Disease

G&H What is the current understanding of the relationship between the gut microbiota and alcohol-associated liver disease? BS Alcohol-associated liver disease is accompanied by changes in […]

A Systematic Approach to Pregnancy-Specific Liver Disorders

Abstract: Consultation for liver disease during pregnancy is challenging for both the hepatologist and gynecologist, as normal physiologic changes during pregnancy can mimic chronic liver disease. […]

Advances in the Management of Renal Dysfunction in Patients With Cirrhosis

Abstract: Renal dysfunction frequently develops in patients with advanced liver disease. Renal dysfunction in this setting is associated with adverse outcomes and an unfavorable prognosis. Hepatorenal […]

Smoking and Liver Disease

Abstract: Cigarette smoking is the leading cause of preventable disease and death in the United States, causing approximately 480,000 deaths per year, which is equivalent […]

Current Management of Alcohol-Associated Liver Disease

Abstract: Alcohol consumption is a major risk factor for various diseases worldwide and is one of the most common causes of chronic liver disease. Alcohol use […]

Lifestyle Interventions Beyond Diet and Exercise for Patients With Nonalcoholic Fatty Liver Disease

Abstract: Nonalcoholic fatty liver disease (NAFLD) is a growing worldwide concern, affecting approximately 30% of the US adult population. Developing pharmacologic therapies for NAFLD is […]

Statins, Fibrates, and Other Peroxisome Proliferator-Activated Receptor Agonists for the Treatment of Cholestatic Liver Diseases

Abstract: Primary biliary cholangitis (PBC) and primary sclerosing cholangitis (PSC) are autoimmune cholestatic liver diseases that commonly result in the need for liver transplantation. The […]

Update on Polycystic Liver Disease

G&H What is the current definition of polycystic liver disease, and what is the genetic basis for this disease? SG We still do not have a […]

Current Treatment of Thrombocytopenia in Chronic Liver Disease

G&H How common is thrombocytopenia in the setting of chronic liver disease? SS Thrombocytopenia is the most common hematologic complication in patients with chronic liver […]

Novel Therapies for Cholestatic Liver Disease

G&H Currently, how is cholestatic liver disease in adults typically treated? CL Cholestatic liver disease in adults mainly consists of primary biliary cholangitis (PBC) and […]

Screening for Nonalcoholic Fatty Liver Disease in the Primary Care Clinic

Abstract: Nonalcoholic fatty liver disease (NAFLD) is a spectrum of diseases ranging from simple hepatic steatosis to nonalcoholic steatohepatitis (NASH) to advanced fibrosis and cirrhosis […]

Thrombocytopenia in Chronic Liver Disease and the Role of Thrombopoietin Agonists

Abstract: Thrombocytopenia is a common complication of chronic liver disease and creates clinical challenges for patients who need invasive procedures. Options available to increase platelet […]

Implications of Nonalcoholic Fatty Liver Disease on Pregnancy and Maternal and Child Outcomes

Abstract: With an estimated 10% prevalence of nonalcoholic fatty liver disease (NAFLD) among women of childbearing age, it is important to understand the implications of this […]

A Practical Review of Primary Biliary Cholangitis for the Gastroenterologist

Abstract: Primary biliary cholangitis (PBC) is an autoimmune chronic cholestatic liver disease characterized by biliary destruction and progressive intrahepatic cholestasis. PBC primarily affects women in […]

Diagnostic and Treatment Implications of Nonalcoholic Fatty Liver Disease and Nonalcoholic Steatohepatitis

Abstract: Nonalcoholic fatty liver disease (NAFLD) affects 75 to 100 million adults in the United States and is the leading cause of chronic liver disease […]

Overview of Updated Practice Guidelines for Pediatric Nonalcoholic Fatty Liver Disease

Abstract: Nonalcoholic fatty liver disease (NAFLD) is a form of chronic liver disease that is characterized by excessive fatty infiltration of the liver in the […]