Optimal Approach to Colorectal Cancer Screening

Abstract: Rates of colorectal cancer (CRC) screening in the United States continue to fall short of guideline-recommended benchmarks. Challenges to increasing CRC screening include racial disparities, […]

Complications of Metabolic and Bariatric Surgery for the Gastroenterologist: A Comprehensive Review

Abstract: By 2035, more than one-half of the global population is expected to have overweight or obesity, amounting to a substantial $4 trillion toll on the […]

Uncovering the Hidden Link Between the Aberrant Intestinal Microbiome and Fibromyalgia

Abstract: Fibromyalgia is a multifaceted syndrome primarily characterized by chronic widespread pain and fatigue. Despite its significant prevalence and incidence, the mechanisms mediating the disease pathogenesis […]

Approach to Meal-Related Nausea and Vomiting

Abstract: Nausea and vomiting are common symptoms that frequently lead to evaluation in the outpatient and inpatient settings. The pathophysiology of nausea and vomiting is complex, […]

Navigating Chronic Pouchitis: Pathogenesis, Diagnosis, and Management

Abstract: Chronic pouchitis affects 13% to 17% of patients with ileal pouch–anal anastomosis and ulcerative colitis, and 20% with a history of acute pouchitis. It is […]

Potassium-Competitive Acid Blockers and Proton Pump Inhibitors: The Dynamic Duo of Acid Blockers

Abstract: The management of acid-based disorders was transformed in the 1980s with the advent of proton pump inhibitors (PPIs), which target the hydrogen-potassium adenosine triphosphatase (proton […]

Management of Overweight and Obesity in Patients With Inflammatory Bowel Disease

Abstract: Increasing evidence has linked obesity to complications of inflammatory bowel disease (IBD); however, data are limited on the efficacy and impact of weight management strategies […]

Noninvasive Assessment to Identify Patients With At-Risk Metabolic Dysfunction-Associated Steatohepatitis

Abstract: Metabolic dysfunction-associated steatotic liver disease (MASLD), previously termed nonalcoholic fatty liver disease, is a major global health issue and a leading cause of chronic liver […]

Alcohol Use Disorder and Alcohol-Associated Liver Disease: New Definitions, Screening, and Treatment

Abstract: Alcohol-associated liver disease (ALD) poses a significant global health burden and is a leading cause of liver-related morbidity and mortality. ALD encompasses a spectrum of […]

Rationale for an Eosinophilic Esophagitis Treat-to-Target Concept

Abstract: Eosinophilic esophagitis (EoE) is a chronic T helper 2–mediated inflammatory disorder of the esophagus defined clinically by the presence of symptoms of esophageal dysfunction and […]

Remote Monitoring for Patients With Inflammatory Bowel Disease: Current Status and the Future of the Field

Abstract: As a direct result of the COVID-19 pandemic, many advances in telehealth have been made that save time and reduce travel costs for patients. Telehealth, […]

Clarifying the Hazy Concepts of Food Allergies and Sensitivities

Abstract: Food allergies, food sensitivities, and adverse reactions to food represent common reasons for gastroenterology and allergy referral. The epidemiology of these disorders is changing; food […]

Diagnosis and Management of Noncardiac Chest Pain

Abstract: Noncardiac chest pain is a challenging condition often encountered by primary care providers, emergency medicine physicians, and gastroenterologists. It is frequently accompanied by persistent symptoms, […]

The Suggested Relationships Between Common GI Symptoms and Joint Hypermobility, POTS, and MCAS

Abstract: An increasing number of reports suggest an association between a newly recognized disease cluster and significant and often disabling gastrointestinal (GI) symptoms. This cluster is […]

Helicobacter pylori Antimicrobial Resistance and the Role of Next-Generation Sequencing

Abstract: Helicobacter pylori infection affects over half of the world’s population and is a global health concern because it contributes to chronic and fatal gastrointestinal disorders, […]

Clinical Guide to Navigating the Landscape of Biosimilars for Inflammatory Bowel Disease

Abstract: Annual out-of-pocket expenditures for patients with inflammatory bowel disease (IBD) are estimated to be as high as $41,000, with medications, such as biologics, being one […]

Family Planning for Patients With Inflammatory Bowel Disease in the Post-Dobbs Era

Abstract: Federal protections for abortion care in the United States ended in June 2022. For people with inflammatory bowel disease (IBD) who are capable of pregnancy, […]

A Clinical Review of Noninvasive Tests for Hepatic Fibrosis

Abstract: Identifying hepatic fibrosis is paramount in managing patients with chronic liver disease. The etiology of liver disease can be owing to many factors, including chronic […]

Is It Time for Noncontinuous Therapy for Gastroesophageal Reflux Disease?

Abstract: Gastroesophageal reflux disease (GERD) is a chronic disorder characterized by the reflux of gastric contents into the esophagus, leading to symptoms and potential long-term complications […]

Leaky Gut Syndrome: Myths and Management

Abstract: Leaky gut syndrome is a condition widely popularized in the lay literature, although it is not currently accepted as a formal medical diagnosis. Multiple gastrointestinal […]