Management of Patients With Refractory Ulcerative Proctitis

G&H What is the current understanding of the relationship between ulcerative proctitis and ulcerative colitis? MC Ulcerative proctitis is part of the disease spectrum of ulcerative […]

Management of Fistulas in Patients With Crohn’s Disease

G&H How common are fistulas in patients with Crohn’s disease, and which patients are at greatest risk of developing them? AL Approximately 25% of patients with […]

Update on the Use of Vedolizumab in Patients With Crohn’s Disease

G&H Based on the research that has been conducted to date, how effective is vedolizumab for the treatment of Crohn’s disease? BB There is strong evidence […]

Targeting Mucosal Healing in Crohn’s Disease

Abstract: The goals of medical treatment for Crohn’s disease are to induce remission and prevent long-term complications. The assessment of disease activity and response to […]

Fecal Diversion in Patients With Crohn’s Disease

G&H What are the main reasons for performing fecal diversion in a patient with Crohn’s disease? FR There are 2 reasons to perform fecal diversion, […]

Use of Vedolizumab for the Treatment of Crohn’s Disease

G&H How does vedolizumab work? BB Vedolizumab (Entyvio, Takeda) works by interfering with lymphocyte trafficking in the gastrointestinal tract. Specifically, it binds to the α4β7 […]

Perianal Fistulas in Patients With Crohn’s Disease, Part 2: Surgical, Endoscopic, and Future Therapies

Abstract: The treatment of perianal fistulas remains a clinical challenge despite the significant advances that have been made in the management of luminal inflammatory bowel […]

Perianal Fistulas in Patients With Crohn’s Disease, Part 1: Current Medical Management

Abstract: Despite significant advances in the treatment of luminal inflammatory bowel disease, the treatment of perianal fistulas remains a clinical challenge. Perianal fistulas are traditionally […]

Highlights From the New ACG Guideline on Crohn’s Disease Management

G&H When and why was the new guideline released? GL The new American College of Gastroenterology (ACG) guideline for managing adult patients with Crohn’s disease was […]