Vedolizumab-Induced De Novo Extraintestinal Manifestations

Abstract: Background: Vedolizumab is an α4β7 integrin antagonist with gut-specific effects on lymphocyte and monocyte trafficking. Although the treatment is beneficial for inflammatory bowel disease (IBD), […]

Perianal Fistulas in Patients With Crohn’s Disease, Part 2: Surgical, Endoscopic, and Future Therapies

Abstract: The treatment of perianal fistulas remains a clinical challenge despite the significant advances that have been made in the management of luminal inflammatory bowel […]

Perianal Fistulas in Patients With Crohn’s Disease, Part 1: Current Medical Management

Abstract: Despite significant advances in the treatment of luminal inflammatory bowel disease, the treatment of perianal fistulas remains a clinical challenge. Perianal fistulas are traditionally […]