Tags: Hepatocellular Carcinoma
Current Status of the Liver Imaging Reporting and Data System in Hepatocellular Carcinoma
G&H What are the current uses of the Liver Imaging Reporting and Data System in hepatocellular carcinoma, and what are its main categories? VC There are […]
Durvalumab Plus Tremelimumab for First-Line Treatment of Hepatocellular Carcinoma
G&H What is the rationale for using durvalumab and tremelimumab in combination for the treatment of hepatocellular carcinoma? RK Durvalumab (Imfinzi, AstraZeneca) and tremelimumab (Imjudo, AstraZeneca) […]
Current Status of Hepatocellular Carcinoma Surveillance
G&H What evidence is currently available showing the benefits of hepatocellular carcinoma surveillance? NP The benefits of hepatocellular carcinoma (HCC) surveillance have been evaluated in several […]
Selective Internal Radiation Therapy Using Yttrium-90 in Early and Intermediate Hepatocellular Carcinoma
G&H How does selective internal radiation therapy using yttrium-90 work? RS Selective internal radiation therapy (SIRT), also known as radioembolization, involves the intra-arterial injection of micron-sized […]
Hepatocellular Carcinoma and Hepatitis Delta Virus
G&H Is hepatitis delta virus oncogenic? NR The simple answer is yes, although hepatitis delta virus (HDV) is not yet labeled as a carcinogenic virus. It […]
How to Choose Second-Line Treatment for Hepatocellular Carcinoma
G&H What are the current options for first-line medical treatment of hepatocellular carcinoma? CF Recently, there has been a significant progression in the options that are […]
Smoking and Liver Disease
Abstract: Cigarette smoking is the leading cause of preventable disease and death in the United States, causing approximately 480,000 deaths per year, which is equivalent […]
Update on the Diagnosis and Treatment of Hepatocellular Carcinoma
Abstract: Hepatocellular carcinoma (HCC) is the fourth-leading cause of cancer-related mortality worldwide and the fastest-rising cause of cancer-related death in the United States. Given the […]
Risk of Hepatocellular Carcinoma Using Tenofovir Disoproxil Fumarate Vs Entecavir for Hepatitis B Virus Treatment
G&H What is the current understanding of the relationship between hepatocellular carcinoma and hepatitis B virus infection? RW Patients infected with chronic hepatitis B virus […]
Current Status of the Use of Statins and Aspirin in the Chemoprevention of Hepatocellular Carcinoma
G&H What are the main risk factors for hepatocellular carcinoma? YH Hepatocellular carcinoma (HCC) almost exclusively develops from underlying chronic liver disease, which is characterized […]
Atezolizumab and Bevacizumab Combination Therapy for Hepatocellular Carcinoma
G&H What are the current first-line medical treatment options for hepatocellular carcinoma? AE-K Two drugs have been approved for the first-line treatment of hepatocellular carcinoma […]
Current Status of the GALAD and BALAD Biomarker Models for Hepatocellular Carcinoma
G&H How has the role of biomarkers evolved in hepatocellular carcinoma? LR Perhaps the most common way that biomarkers are being used is to aid […]
Overview of Ablative Therapy for Hepatocellular Carcinoma
G&H What is the role of radiofrequency ablation and microwave ablation in the treatment of hepatocellular carcinoma? SR Both radiofrequency ablation and microwave ablation are […]
The Gastroenterologist’s Guide to Preventive Management of Compensated Cirrhosis
Abstract: Despite advances in medical care, the prevalence and mortality associated with cirrhosis continue to rise. The majority of medical care and physician efforts are […]
Current and Future Systemic Therapies for Hepatocellular Carcinoma
Abstract: Hepatocellular carcinoma (HCC) is a common cancer with unmet needs and limited effective therapeutic options. The management strategy for diagnosed HCC is based on […]
Statins and Hepatocellular Carcinoma Protection
G&H What have studies found regarding the possible relationship between statins and hepatocellular carcinoma protection? DK Approximately 10 years ago, the first large study looking at […]
Care of Patients Following Cure of Hepatitis C Virus Infection
Abstract: The vast majority of persons with chronic hepatitis C virus (HCV) infection will achieve virologic cure with the current direct-acting antiviral therapies. Prevention of […]
Treatment of Hepatocellular Carcinoma With Lenvatinib
G&H What is the mechanism of action of lenvatinib? K-HH Lenvatinib (Lenvima, Eisai) is a tyrosine kinase inhibitor selectively targeting vascular endothelial growth factor receptor […]
Drugs in Development for Hepatocellular Carcinoma
G&H What have been the most recent advances or changes in hepatocellular carcinoma drug development? LR For approximately 10 years, the only drug available for […]
Gastro-Hep News
US Food and Drug Administration Approves Lenvatinib for Hepatocellular Carcinoma On August 16, 2018, the US Food and Drug Administration (FDA) approved the kinase inhibitor lenvatinib […]