Efficacy and Safety of Dual Biologic Therapy in Patients With Inflammatory Bowel Disease: A Review of the Literature

Abstract: Using 2 or more treatment modalities to achieve a synergistic effect in patients with refractory inflammatory bowel disease (IBD) has been an area of focus […]

Vedolizumab-Induced De Novo Extraintestinal Manifestations

Abstract: Background: Vedolizumab is an α4β7 integrin antagonist with gut-specific effects on lymphocyte and monocyte trafficking. Although the treatment is beneficial for inflammatory bowel disease (IBD), […]

Extraintestinal Manifestations of Inflammatory Bowel Disease

Abstract: xtraintestinal manifestations of inflammatory bowel disease are prevalent in both ulcerative colitis and Crohn’s disease. The most common manifestations involve the musculoskeletal and dermatologic systems. Other manifestations involve the hepatopancreatobiliary system (eg, primary sclerosing cholangitis) as well as the ocular, renal, and pulmonary systems. A multidisciplinary team approach is often needed for effective management, and emergency situations require prompt evaluation.